Insist on Mass Spectrometry (MS) Detection
The detector is the single most critical component of an analytical instrument and is directly responsible for the accuracy and reliability of the analysis. However, not all analytical instruments are created equal. Most low-end instruments are paired with spectrophotometry detectors such as a UV/Vis detector.
The major disadvantage of spectrophotometry detectors is its inability to discriminate between the target analyte and other interferences, such as chromatographically co-eluting impurities. In addition, the low sensitivity of a spectrophotometry detector is often inadequate for trace-level quantification of analytes.
In contrast, mass spectrometry detectors, such as IALR’s Waters® Triple Quadrupole detector and Quadrupole Time of Flight detector, provide unparalleled sample specificity and sensitivity. Our instruments are able to use an analyte-specific chemical fingerprint, known as a mass spectrum, to pinpoint and distinguish the target analyte from interferences, thereby allowing unequivocal identification and accurate analysis. Also, mass spectrometers provide much wider dynamic range, enabling accurate analysis of analytes across a wide concentration range.